I have small fiber PN (idiopathic) and take 3600mg of Gabapentin and my neurologist added 60mg of Cymbalta. I had profuse sweating and found it very uncomfortable. I switched down to 30mg and though I still have some sweating its tolerable. Whether any of these have made my PN any better is up for debate, but i still take them faithfully.

On a side note: They tried me on Nucynta 50mg (for pain relief) and it put me into LaLa land, so they had me go onto try a 1/4 tablet and i tolerated it better and saw some pain reduction. Then i went up to 1/2 of a 50mg pill and several days into that step up plan I had a seizure and ended up in the ER. So no more NuCynta for pain relief and back to Oxycodone 7.5/325 for pain as needed. Last night I had to take two to make the burning tolerable so i could get to sleep.

What a frustrating process.

Doc