they are finding the 'receptors' that send the signal. But, not yet know what is triggering the receptors to scream HOT or COLD? Next step, not know what to do about turning off those receptors yet? Essentially, they've discovered one more of the many 'processes' in the whole set of processes?

I'm wondering out loud here in that those folks w/PN have either/and/or Hot and cold sensations at once. Folks w/MS by contrast, tend to have more of the HOT sensations...even tho their demeylination occurs mostly in the brain as opposed to the extremeties. Are these receptors site specific to the peripheral nerves or thruout the body?

I'm just wondering out loud here. I wonder what will be next, and where it all will lead us. I for one just want it all {RELIEF!} soon. - j