Well, the test for high manganese came back with normal levels, which was what we really expected, altho it was nice to hope for a little while that the PD symptoms could have been due to a blood abnormality! We have now cut back another half pill and amazingly I am seeing bits of his old personality come back - Yahoo!! Two other friends have said something similar recently, not knowing that we have been gradually decreasing the mirapex. So i am a definite believer in this drug being the cause of his personality changes. As JohnT commented earlier PD affects the entire family, and I am responding positively to the changes I see in him so its been a win-win situation.