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Senior Member
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Join Date: Aug 2006
Location: "all the way over on the West Coast"
Posts: 1,032
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Senior Member
Join Date: Aug 2006
Location: "all the way over on the West Coast"
Posts: 1,032
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I think any trial, patient-designed or other, is fatally compromised before it starts because we still don't know what Parkinson's is. Any trial cohort is diluted with people who don't have PD, or have different manifestations of PD.
Until we get some identifiable biomarkers, all else is speculation - influenced by the too-hard-to-control placebo effect (especially by those who are testing their own reaction to pills taken with orange juice).
If we have learned anything from taking sinemet for so many years, it is that symptom control has little to do with halting progression or curing the disease.
A fix for Parkinson's lies beneath the surface; taping before and after downing our pills with OJ will tell us only what we want, or don't want, to believe.
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Carey
“Cautious, careful people, always casting about to preserve their reputation and social standing, never can bring about a reform. Those who are really in earnest must be willing to be anything or nothing in the world’s estimation, and publicly and privately, in season and out, avow their sympathy with despised and persecuted ideas and their advocates, and bear the consequences.” — Susan B. Anthony
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