The first study was extremely narrow in its scope. It is far from indicative of any benefit. The Controlled Cortical Impact is a poor attempt at a concussion.

The second article is about Parkinson's Disease. This is not applicable to concussion either.

Neither article establishes any guidelines for a therapeutic use of nicotine.

If you are having a hard time finding your way from room to room in your home, maybe some nicotine will help. BUT...... I doubt that is your problem. The mouse brain has a similar cell structure to the human brain but the processing of information is much more primitive in a mouse.