One of my doctors put me on this and started me on a 25mg dose and told me that we were going to gradually increase the dose. Like clockwork I got VIOLENTLY ill 30-45minutes after taking the Cymbalta. I tried for 3 days (with food, without food, etc) and then called the doc and was told to stop taking it. When I stay violently ill I mean worse than anything I have ever experienced with projectile vomiting and it coming out both ends at the same time...worst experience of my life and it was when I couldn't stand or walk at all and was home alone the first time it happened. I was so scared when it happened the first time.

I later found out that I had serotonin syndrome when I tried taking the Cymbalta...which might account for the terrible reaction to it. Never tried it again though as that was about the time I went off all meds (after the serotonin syndrome diagnosis).