I take Cymbalta and Tramadol along with some supplements. I also get IVIG Rxs. i currently get the Rx once a month but my neurologist and rhemo are talking about increasing them to 3 days in a row each month. This seems to work for me. I'm not pain free but better then I was. I use to live with a 9-10 on the pain scale now there are days were I am a 4-5.