Lab Rat, trading rigidity for tremors doesn't sound like a good deal to me. I had been thinking of taking it to see if it would help my tremor dominant parkinsonism. What degree of tremor did you have before taking isradipine (dynacirc)--did you have no tremors before or just a little bit that didn't interfere with adl's or what? MJFF website announced back in July 2012 results of clinical trial of isradipine insofar as dosage safety is concerned with a plan to move ahead with a stage III trial which would focus on efficacy. I was encouraged by this because elsewhere I think I had read that it could help w/tremors. That's why I'm taken with your account of it inciting tremors that you may not have had otherwise....