I don't mean to offend you at all but heading down the immunosuppressant road is like putting the cart before the horse.
Do you believe you have been thorough diagnosed for everything that is going on with you? If not, maybe you too need more doctoring.
We've already had this discussion about cancer and immuno's. If cancer runs in your immediate family or you've already had it, they are contraindicated.
More isn't always better. Drugs are useful but they can make you worse.
You really need a smart internist who can pull of this together for you. Do you have one? Did you ever find out why your blood was so dark (it was you, right?).
Ditto on the port. Though I know you are also at risk for infections. And a port can cause issues with clotting, which is also a concern for you.
I hope you will consult more doctors to find answers before you look for solutions. I don't envy the situation you are in.

Annie