Mona - I have been on it for awhile - cannot tell if it helps. I have whole body nerve pain from CRPS. I literally burn from head to toe. It is terrible. I am on c-naltrexone 10mg, 3,300mg gabapentin, 20 mg cymbalta, 60 mg dextromethorphan per day. What is the rest of your CRPS med regime? take care,