I haven't tested postive for any antibodies but clinically was I thought diagnosed with MG. My neuro opthomologist believes I have MG based on my symptoms (constant double vision, droopy eye lid, throat numbness/weakness, difficulty getting a full breath, excessive salivation and left leg weakness) and asked that my neurologist start treating me for it. Neuro started me on some predinisode with tapering down to nothing and Cellcept. I noticed no differance and asked him to give me a trial of Mestonin. He did reluctantly but said that if I had MG the other treatment should have worked and wanted me to see a neuro muscular specialist for a second opinion.

Mestonin does help some - I say about 50% differance on some of my symptoms, but not the double vision and it wears off quickly.

The neuro muscular specialist my neuro referred me to says I should consider eye surgery since treatment is not working for MG. He did find some muscle weakness in my exam and wants me to have an EMG with him later this week. I had one done last summer that was negative.

My concern is - 1, I do not have MG and I'm taking all this unnecessary medication or 2 - I do have MG and we are talking about eye surgery.

How confident are you in your seronegative diagnosis?