I've been meaning to post something here for some time now, but have been waiting for something positive to share. As of yet, I have nothing productive to report as regards to anti-mag igm neuropathy, which is my present diagnosis. I have a strong medical background as well as integrative knowledge. I've been to a couple of international symposiums on autoimmune diseases and demyelinating neuropathies. My perception and/or experience tells me that IGIV, prednisone, and rituximab have little chance of helping anti-mag patients. On the alternative side of things, the perception that the immune system is based in the gut, would lead one to hope that supplements such as probiotics, glutamine, DGL, aloe, green tea, etc. might help. One might also suppose that avoiding those foods, dyes, herbs, etc. that sensitize your immune system such as gluten, dairy, ... might be advisable. Alcohol is a neurotoxin of sorts- limitation advisable? Alpha-lipoic -neuroprotective. Co-Q-10- potentially neuroregenerative? Fats in diet and omega-3 to provide raw material for myelin? I thought that by now I'd happen upon something helpful- been trying real hard for almost a year. I feel that my progression is fast- seems on a daily basis I lose more feeling and balance in feet and legs. Fingers constantly tingling with handwriting affected. Am presently pursuing mind-body connection - some really interesting books on the subject. Have not seen anyone mention pursuing treatment with a functional medicine physician- looks for a cause and reason for what's happening- not just hanging a label on what you've got and handing you a drug or prescription. Have to have a genetic predisposition for this to have happened- I believe it's the trigger that sets it off that is key to understanding it all. When and if I finally stumble upon that elusive unknown that might help one or more of us, I'll be sure and let you know. My best to all of you- I know EXACTLY what it feels like- both physically and emotionally.