I'm still confused.

What is the relationship between this work and using liposomes to get drugs through the BBB?

The work we're discussing here was published in ACS Nano earlier this year [1]. Mazza et al. present "a peptide brain delivery strategy using peptide drug nanofibers as a concept and show that self-assembling peptide drugs, which give rise to nanofibers, are able to deliver the model peptide dalargin to the brain and elicit a pharmacological response."

To answer my own question, I understand this to be an alternative method to using liposomes to create drug carrying nano particles that cross the BBB.

In my opinion too little effort has been put into translating earlier work into practical drug delivery systems. For instance, it was known 15 years ago that liposomes could be used to get dopamine through the BBB (see a thread started by moondaughter last year [2]). Whatever happened to that?

References

[1] "Nanofiber-Based Delivery of Therapeutic Peptides to the Brain"
Mariarosa Mazza, Rebecca Notman, Jamshed Anwar, Alison Rodger, Matthew Hicks, Gary Parkinson, Dave McCarthy, Tina Daviter, Julian Moger, Natalie Garrett, Tania Mead, Michael Briggs, Andreas G. Schätzlein, and Ijeoma F. Uchegbu
ACS Nano20137 (2), 1016-1026
http://pubs.acs.org/doi/full/10.1021/nn305193d

[2] http://neurotalk.psychcentral.com/sh...ight=liposomes

John