Hi There! Oooooh YES! Immodium has been my dear friend for almost five years now. The Mestinon caused me to have it alot. My dosage of Mestinon has been reduced now and I deal with the MG symptoms more but, not as much discomfort. I have found that you need to experiment with it and see what works for you. I would recommend that you don't exceed the daily dose of Immodim. Hope this is an encouragment.