I think I would lean towards the least amount you can get by with, if it were me... Not that I have all that much knowledge about Meth, but the 1 pill I took about knocked me into next week, not to mention making me throw up all night long... I could have gotten by with probably a fourth of that pill, maybe even less. The friend who gave it to me is on a VERY heavy duty pain regimen.

Besides, at some point you may need to be on a higher dose and I would think you would want to leave some room there in case you need to increase.

Cathie