Hi, pebblebeach2,

I'd like to suggest you read this post of mine from the past:
http://neurotalk.psychcentral.com/post15298-4.html

Methadone is useful for many chronic pain patients, and is very
popular therefore.

However, if you have a hidden cardiac rhythm problem, it can
cause prolonged QT syndrome, and sudden death.
So it is a good idea to get an EKG before starting and have
the QT interval measured.

Another drawback is that Methadone has a long 1/2 life in the body and will fall off the pain receptors, first, and therefore be still active elsewhere for a time. The result can be getting another dose too soon or raising it to make up for this, and then the drug builds up and can affect the heart with more risk.

When people are converted over from other opiates, errors can be made so make sure your doctor uses a conversion table, for this. Giving too much methadone therefore when switching may cause a problem in some patients.

This link has a conversion app for example. But there are others too.
http://www.globalrph.com/narcoticonv.htm

Once these problems are looked at and you are cleared of them, you could see good results.