That sural nerve biopsy can leave you with permanent PAIN...
as well the numbness.
The conduction tests should show if you have axonal problems.
The sural biopsy is rather redundant and not done much anymore.
What blood pressure drug do you take? Some can cause
drug induced lupus, or other reactions. I am recovering from this from my ACE inhibitor.
This link gives drug induced lupus triggers. This condition does NOT raise ANA values, and can go undetected, by common testing.
http://www.lupus.org/webmodules/weba...=377&zoneid=17
Never underestimate your medications. Doctor still do, but you should not. And I am lucky I figured out my own problem, when I did. It was agony.
Some people who take beta blockers develop a myopathy.
Here is a paper on this:
Quote:
Baillieres Clin Rheumatol. 1991 Apr;5(1):21-38.
Drug-induced myopathies.
Le Quintrec JS, Le Quintrec JL.
Abstract
Myopathies are not an unusual complication of drug therapy. The major symptoms in drug-induced myopathies are proximal muscle weakness, increased muscle enzyme levels, electromyographic changes and histological lesions. Some drug-induced myopathies are associated with neuropathy. Drug-induced myopathies can be classified according to the presence or absence of muscular pain and associated neuropathy. Among painless myopathies, we can distinguish myopathies without neuropathy (corticosteroids), myopathies with neuropathy (colchicine, chloroquine and hydroxychloroquine) and myasthenic syndromes (D-penicillamine, antibiotics, beta-blockers). Among painful myopathies, the classification is similar: painful myopathies may or may not be associated with neuropathies. Painful myopathies include polymyositis (D-penicillamine, cimetidine, zidovudine) and other myopathies without polymyositis (clofibrate, statines, cyclosporin). Among the painful neuromyopathies, eosinophilia-myalgia syndrome is a recently described disorder associated with the use of L-tryptophan. Combinations of drugs (for example, a fibrate and a statine or cyclosporin and colchicine) can induce severe myopathies. If such drugs are used together a vigorous surveillance to detect any sign of myopathy is warranted. Instead of classifying drug-induced myopathies according to clinical features, a histological classification can be proposed. Many drugs can induce vacuolar myopathy (colchicine, chloroquine, amiodarone, cyclosporin, drugs causing hypokalaemia and lipid-lowering agents), some others cause a mitochondrial myopathy (zidovudine) or a necrotizing myopathy as seen with vincristine. Overall, several criteria for reporting drug-induced myopathy can be recommended: lack of pre-existent muscular symptoms, a free period between the beginning of the treatment and the appearance of symptoms, lack of another cause accounting for the myopathy, and complete or incomplete resolution after withdrawal of the treatment. Rechallenge of the treatment is not advisable because of the risk of a serious relapse. The exact mechanisms by which drugs cause myopathies are unknown. Some cases may be due to metabolic changes, whereas others may be immune mediated. Nevertheless, the aspect these conditions have in common is the regression of the myopathy with the discontinuation of the drug.
PMID:
2070426
[PubMed - indexed for MEDLINE]
|
from
http://www.ncbi.nlm.nih.gov/pubmed/2070426
You need your B12 numbers because lab ranges in US go down to 200, which is low enough for damage to occur. This is not flagged by labs, still today, so you may be low and not know it.
This is very important. And we see it here frequently.
Cryoglobulinemia:
http://en.wikipedia.org/wiki/Cryoglobulinemia
When the blood cannot flow into the little blood vessels in the tissues, the nerves may starve and die.
You might want to soak in warm water with magnesium, in the form of epsom salts. This will open up your blood vessels and improve tissue perfusion. Don't use really HOT water, as that may sting your skin. See if this helps. If so using a good magnesium product that is absorbed well, orally, will help further. Some natural VitE is also helpful for poor circulation.
At least 400IU a day. Fish oil or Krill oil is very good too. So please consider those.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
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Weezie looking at petunias 8.25.2017
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