All the best to you & your wife sddave. I can sympathize with her pain, being in the midst of it myself. It's a horrible feeling to never be able to get completely comfortable & to have life's little things taken away due to pain (I never thought I'd miss doing laundry!) Please know that my thoughts are with you & everyone suffering from this puzzling ailment. I'll be sure to keep you all posted if I have any success with my new vitamin/diet regimen.