I did not find any comments about S-100b protein in the etanercept articles. There are a number of weaknesses in the reports. They are open label meaning they expose the subjects that have taken the etanercept injection. They note quick improvements but I could not find any data for how long the improvements last. It also requires an injection into the

The contra-indications of TB and any immuno-compromised conditions make it a bit scary. The cost makes it unlikely for all but the worst injuries. If the Enbrel can be administered by a caregiver after an $800 training in Nicaragua, the minimum cost is $200 per week that may be extended to $200 per month at the very best. Every 2 weeks is more likely a optomistic outcome. Injections into the fatty tissue between C-5 and C-6 every week creates a risk. I would expect administration by a doctor or other licensed professional would easily increase this cost to $1000, considering malpractice issues. The protocol requires 12 weeks as a test phase although 4 weeks can be a minimum test phase in some cases.

The objective with very early stage Alzheimer's Disease is to get an improvement equal to 1 to 3 years prior to treatment date. Those of us who have seen the very early stages of AD recognize this as a recognizable but minor improvement.

This sounds more like an attempt to find new markets for a very expensive drug than a protocol that will gain approval by many payers.