Hi,
Be patient. As Crmak siad, it takes time. It took me 1 year to notice a gradual improvement and 1 1/2 years to get full benefits. Every time I increased I was hit with a lot of nausea for a bout 3 weeks and then it went away. I take 3500mg daily with no side effects. Hope it is successful for you - I took Imuran for many years and it did not work at all compared to the cellcept.