Quote:
Originally Posted by amike
... the "AlkaSeltzer Trick." It sounds like something out of James Bond.  Is there a string you could point me to that discusses the specifics of the AT? (like when to take, what to look for?, etc,)
I am on Ramipril 10mg for hypertension. I'm not sure if that is an ACE inhibitor.
I'll try and post something in the new members section over the next day or two, as I am new to the board and just started posting in out-dated threads.
Thank you!
Mike |
YIKES....you are using an ACE inhibitor and have PN symptoms?
That is a sign to get that drug changed. I am recovering from Lisinopril, which became so toxic I was having a nightmare suddenly of severe severe pain and swelling. You can get swelling in your throat suddenly, as the bradykinin builds up and have a major emergency! I'd discuss changing the drug immediately and see if your symptoms improve. I am suspecting they will.
On top the bradykinin elevation, I also had a drug induced lupus from the ACE inhibitor which made my joints inflamed and also
created a mysterious rash on both my forearms.
Your specific ACE inhibitor also can cause liver damage. Another reason to get it changed.
Please consider this, as it might fix your problems.
bradykinin:
http://en.wikipedia.org/wiki/Bradykinin
People vary in how they metabolize this bradykinin away.
Bradykinin reactions in normal people are called acquired angioedema. But if you have a genetic error in this metabolism, you could have another form of angioedema which makes you most sensitive and likely to have reactions.
This is called HAE..
http://www.haea.org/
I think anyone with PN taking an ACE inhibitor is at risk of this buildup of bradykinin and hence symptoms of that.
It took 10 yrs + for my reaction to go ballistic. So time means nothing if you have been on these drugs for a while. I am now on a very small dose of beta blocker which is working so much better on my BP and has no side effects!
As far as AlkaSeltzer goes just take one packet of two and see if things get better. If it does, that points to inflammation as a PN component. This form of aspirin is pretty safe because it is in
solution and therefore absorbed very quickly and doesn't hang around the stomach to irritate anything. If you use any blood thinning drugs, or have stomach ulcers you need medical
permission to use any aspirin product.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
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Weezie looking at petunias 8.25.2017
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