Skywalker I think you would be surprised with how much some doctors understand, particularly if it is a known and relatively common side effect. A history of depression was one of the reasons why I was put on Copaxone instead of Rebif since we knew it would be a possibility.

It may cost money to see a doctor, but it doesn't to pick up the phone and call. Just say that you want to speak with the neuro or nurse practitioner about depression after taking Rebif and somebody should call you back if they can't speak with you then. It can be serious and warrants looking into. They may want to change what you are on or have you take something to go with it.

I know that it is easier to talk to random people online, but even as a psychologist I can't help you much through the internet other than offer you the serious advice to call your doctor...