Welcome to NeuroTalk:
What other drugs do you take? Any ACE inhibitors for blood pressure?
Gabapentin can cause fecal incontinence in some people.
Also some of your other symptoms, like the shortness of breath.
I am recovering from a drug induced lupus from an ACE inhibitor and I had many of your symptoms. Drug induced lupus does not elevate the ANA blood work....so blood work may appear "normal"
Do you have any swelling? Spells...like you describe can be from angioedema also, which is acquired from ACE inhibitors or can be present from birth (genetic). Bradykinin builds up in the body, and causes edema of the internal organs, shortness of breath,
GI pain, burning sensations, and sometimes swelling of the hands/feet/stomach, etc. This is due to a lack of an enzyme that metabolizes bradykinin away.
Here are some links...
http://www.haea.org/
http://www.haehope.com/hae-attacks/p...e-attacks.html
http://www.hcplive.com/publications/...-04/2005-04_02
One of the less common forms of angioedema is connected to estrogen use in females.
Also angioedema does not always have hives. That term is also used for hives, and can be confusing. Hives are mediated by histamine. Angioedema is bradykinin induced...which is a different biogenic amine. Angioedema is difficult to diagnose, and often patients do not get proper care. There are specific blood tests to show the various types. The cycling of "spells" or "attacks" suggests this however for you, combined with the lack of lesions on MRI.
Another thing to check is your B12 level. This should be above 400 pg/ml (US units). Low B12 will affect the nerves all over the body, and can be confused with MS symptoms and other things.
It is estimated that 40% of adults in the US are low, because of heavy use of acid blocking drugs, or other medications, vegan lifestyle, or hereditary loss of intrinsic factor in the stomach.
Many of your symptoms resemble low B12 situations. One characteristic test is Romberg's sign. If you cannot stand upright alone with your eyes closed, this suggests you need testing ASAP.
Test ranges are outdated, and go very low, and do not reflect the new protocols that are about 10 yrs old now. So don't accept "normal" from your doctor, get the actual result and post it here.
If you are in another country post the concentration as well as the numbers. pg/ml, nmol/L ? ng/L ? We've seen on these boards people who were going to many doctors and none of them received proper testing or treatment for very low B12 levels!
Here is a new video illustrating what low B12 can do to your body:
http://www.youtube.com/watch?v=BvEiz...ature=youtu.be
And this is my B12 informational thread:
http://neurotalk.psychcentral.com/thread85103.html
The MS experts will come on here and address your MS questions specifically. I can only address other issues for you.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
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Weezie looking at petunias 8.25.2017
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