hi, i had read about not mixing cymbalta and neurontin on a cymbalta info page, not sure if it was wed md or the rx page but my pharmacist agreed and when i went for mt last doctor's visit my doctor mentioned it to me. i do not believe it was a known fact when cymbalta first came out because i know when i used it i had read a lot on it first and never saw it. i think it is one of those things that they 'figured' out as people used it. and lyrica too ... whew. that is a lot of medication. i do hope it is helping you. joan