Interesting Barb. I saw my neuro this week too. I'm doing well on Tysabri but asked about Tecfidera. He said that he has patients that have gotten diarrhea on the drug - a couple of people have bad cases including one gentleman who stopped it because it was so severe and the anti-diarrheal meds weren't
helping even after 3 days off the drug.

He also said that Biogen's claim that the drop out rate from the clinical trials was low because side effect profile was low is a misleading statement. He said the side effects are so obvious (diarrhea and flushing) that people instantly knew they were on the drug. If this was their last chance for help or they wanted to get the drug in the trial, they would tough out the side effects to stay on it. I thought that made sense!

Anyhow, I'm just glad I don't have to contend with a possible new side effect profile!