When I started prednisone, my symptoms got much worse. I could not even tolerate 40 MG. we tried 30 for a few weeks, but it was awful. I am now in the process of getting off prednisone and on cellcept. The transition will take six weeks, but my doctor said it was clear prednisone was not my friend. He was not sure what was true MG issues and what was prednisone. I am at 20 now and feel better, but can't wait until I am totally off of it and just on cellcept. Hopefully the meds are the bigger source of your issue and your dr can find a better solution.