I was given a generic last November and didn't realize that there could be such problems. I experienced 4 to 6 hours of nausea every day for about four weeks before it occurred to me that perhaps the problem was the switch to the generic. I tried to switch back to the original drug but that didn't work either. So I went to Neupro instead of ReQuip XL and the patch worked great except that the first month of the drugs cost $500 and after that it was $200 a month instead of the cheap Requip XL. I used the patch for three months and, hoping that my system was cleared, I switched back to Requip XL about three weeks ago and I am just fine. But it was a darn scary experience.