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Old 05-06-2013, 01:38 PM
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mrsD mrsD is offline
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mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
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This explains it better I think:

http://en.wikipedia.org/wiki/CYP2D6

click on any blue fonted drug and it will explain in its own wiki article:

tramadol:
http://en.wikipedia.org/wiki/Tramadol

It is not as simple as your quote... since tramadol is metabolized by 3 different enzymes.
Quote:
Tramadol undergoes hepatic metabolism via the cytochrome P450 isozyme CYP2B6, CYP2D6 and CYP3A4, being O- and N-demethylated to five different metabolites.
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