I had one back in '11. I'd already been diagnoses, so I am uncertain about whether lesions show up in your lumbar test are enough to dx you with MS?

I had an ok experience with it. I didn't find it painful. I came home and took a nap. Took some naproxen for the headache, more preventative for the headache they mentioned could come with the after effect of having the spinal tap.

There were lesions discovered there. Go along with the lesions on my brain that were discovered in my MRI's.

Best of Luck on your LP.