I get severe pains in my hands. Gets so bad at times it feels like my hand bones are about to break. I have never had good luck with OTC meds for this, and have been taking baclofen and tizanadine for the pain, but its not working well anymore. I have had MS for 21yrs now, and the first 19yrs was pain free. Seems MS is making up for lost time with the pain for me. There are no more pain free days for me, but as everyone knows, each person is an individual and MS hits everyone differently. Hope you can find something that helps with your pain.