Originally Posted by edwinlgreen

For the Prilosec question,
I have tired easy for most of my life. It has gotten worse over the last 20 years. I love to walk and can do so for miles as long as it is a level walk. If I try to walk up or down an incline however I tire almost immediately.
About 15 years ago I was diagnosed with a hiatal hernia. I had acid reflux from that. I have been on acid reducers since then, mostly Prilosec but Nexium for a while. When Prilosec went OTC I switched back. When the doctor wanted to increase my dosage I had him write a prescription. When I complained of being excessively tired he prescribed Synthroid. Said my levels were marginal but synthroid levels are not a one size fits all or something like that. When that did not resolve the problem he doubled the synthroid. After that I just stopped complaining.
A few years ago I started getting severe cramps in my lower right leg if I drove for any distance. When it got to where it happened on just a 10 mile drive to work I starting searching on the internet. Some users sites had reports that b12 helped some users. I also learned that b12 was hard to absorb and you couldn't easily get to much. I already knew that acid reducers affected absorption. When regular B12 did little I switched to subliminal (dissolve under the tongue). That appeared to resolve the issue. When the symptoms subsided I would stop the B12. Every year or 2 when they first seemed to reappear I would take B12 again for awhile.
I wondered if the MG had been around for a long time and was causing the muscle pain in my leg. I also wondered if B12 could reduce the symptoms of MG.
One more point. I have read that emotional events could bring on MG. I have had a couple of very emotional periods in my life.
In 1991 my oldest Daughter was a murder victim. She was shot in the face with a shotgun by a would be carjacker. My life long symptom of tiredness and over all aches and pain hit a new level after that.
I spent most of 2012 at Duke medical center watching my 3 year old Grandson die from Late Infantile Medocramatic Leukodystrophy. He was diagnosed in January. He spent 5 months under going a stem cell to bone marrow transplant. In December on his 5th trip back to the hospital he died from complications of MLD complicated by the effects of the transplant. My external symptoms of MLD stared about 4 months after his death.