--between peripheral neuropathies, especially those that are small-fiber predominant, and reflex sympathetic dystrophy/complex regional pain syndrome/erythromelalgia (there's some dispute as to whether the latter are actually different clinical syndromes or all aspects of the same one), but there are also some differences in the differential diagnosis. The major ones are that the latter syndromes are more often associated with a partiuclar traumatic event, and that they are usually associated with trophic changes in the skin as well, which is not generally associated with peripheral neuropathy.

They both may be associated not only with burning, stabbing pain and with autonomic dysfunctions, and yes, many of the same meds are used for symptom relief in both.

Since overactivity and inappropriate signal maintenance in the sympathetic neurons is thought to be one of the mechanisms involved in RSD/CRPS, one treatment that is often tried early in the course (if one can do it in time) is sympathetic nerve block, a treatment not normally done for diagnosed peripheral neuropathy.