--for those afflicted with peripheral neuropathy, especially those whose neuropathy stems from diabetes or other conditions (and there are a lot of them) that affect the small, thinly myelinated and unmyelinated fibers, which include the autonomic or involuntary nerve responses. In addition to the actual damage to the nerve fibers the nitric oxide pathways are often disturbed in these conditions and lack of circulation allows metabolic toxins to build up and prevents vital nutrients and oxygen from getting into the areas in the concentrations they should.

Of course, it's often hard to ascertain to what degree the dysfunction is due to the neuropathy processes and to what degree it's due to any one of many other factors that can contribute to it--particularly the circulatory compromise we have a tendency to get as we become older.

As such, anything that helps nerves and circulation is likely to be helpful for the dysfunction, though nothing is a panacea. Particularly essential fatty acids such as found in fish, flax or krill oil are recommended, as is as much exercise as is tolerable.