I want to add my voice. I tested negative for AChR antibodies three times, negative for LEMS and MuSK once each. I was diagnosed with MG by my third SFEMG.

Look at all of us seronegatives. I really think the number is much higher than 10%. I bet that many people with seronegative MG don't get diagnosed, so they're not counted.

My neuro said to me the other day that he thinks I probably have antibodies we haven't discovered yet, directed against one of the other proteins in the neuromuscular junction. One clue is that I don't respond at all to Mestinon.

The way I got diagnosed when my neuro wasn't willing to pursue the matter was to ask him to refer me to someone who specializes in MG. He was happy to do it. He sent me to Boston (an hour and a half away) to Dr. David Weinberg, who does a special kind of SFEMG (stimulated).

Abby