I don't know how helpfull this will be for you but here is my experience. I have been sick for a long time but became so ill 7yrs ago that I could not get out of bed to go to work. during all these years anytime I was on prednisone I felt so much better, grant it they were always the pred dose packs, I think it is 10 days tapered down. I was dx with mg in Jan. of this year, in March I was given 50mg pred every day, the first week I felt like a champ, then it spireled out of control and i haven't been able to gain any ground since. My mg is the worst it has ever been, all those years I just knew pred was the answer, now i don't know if there is an answer. I wish you well and hope you have nothing but a perfect experience with the pred.