Hi, the withdrawl from Ultram is horrible. Its a nightmare. And I became very depressed. Eyes glazed over and I could not get off the couch. It was horrible. I stayed like this for 5 days. Then my Neuro put me back on it. I am on 200mg a day. It does help with the nerve pain and twitching and pins and needls. I would much rather stay on it at a low dose and be comfortable than be miserable.