Thanks for the reply! I've been on Cymbalta now for a bit more than 5 weeks and my next appointment is the end of July. Since I've had this PN for 13 years, the relief I've got now from the pain is dramatic for me. Even "mildly discomfortable" is amazing.

I don't have the test results myself, but my neurologist specifically mentioned the B12 as being normal because 'd specifically mentioned this when I first spoke to her before the tests were done.

I have no real problems with the no-orgasm thing for another few weeks - it's not like my libido has evaporated -quite the contrary- and as long as my wife is ok with this, there are a lot worse things I've been through.

But I will discuss this Wellbutrin with my neurologist and see what the downside of that might be.