My husband was on Apokyn before he had DBS. It was amazing and we were so grateful to have it. We would go out to dinner and he would freeze and not be able to get out of his chair. A quick shot of this and he was up and running again almost immediately. The trick is, you learn to dress so that your belly is easily and discreetly accessible. I had to give the shots because when he needed them, he was too nonfunctional to do it himself. He suffered no ill effects from it's use. Some folks experience nausea but he did not have that problem. Great stuff! In Europe, you can get a pump but as far as I know only injections are available in the US.