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Old 06-14-2013, 07:27 AM
glenntaj glenntaj is offline
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Join Date: Aug 2006
Location: Queens, NY
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glenntaj glenntaj is offline
Magnate
 
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
15 yr Member
Default One would not think--

--that muscle wasting would be involved in a predominantly small-fiber neuropathy, as the small fibers subsume the sensations of pain and temperature and do not ennervate muscle.

If there is muscle wasting as well that implies there is also large fiber involvement of some sort. Large, myelinated fibers include all motor neurons as well as those that involve the sensations of mechanical touch, vibration, and positioning in space.

Of course, one can get some degree of muscle wasting just from lack of exercise, which happens to a lot of people with debilitating conditions. The trick is to see if it related to the condition itself as opposed to a secondary effect.
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