Quote:
Originally Posted by cait24
No, I had it too. It started with the MG 2 years ago and never went away, even for a second. It got worse as the day progressed and on days when my MG was bad. I also was hypersensitive to loud noises and would jump or be startled at noises that did not bother anybody else. I tried doing a lot of research on line about it. the best I could find where the following 2 scenarios and I do not know if either are correct:
1. there are small muscles in the inner ear affected by MG causing the tinnitis
2. There are ganglionic (not muscle) ACHR that affect the Autonomic nervous system including hearing, tinitus, balance and vertigo as well abdominal function, heart etc
thanks
kathie
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Ganglionic ACHR is different than Muscle ACHR. Positive muscle ACHR antibody causes MG. Positive ganglionic ACHR antibody causes AAG - autoimmune autonomic ganglionopathy. I found an article that MG patient after 3-5 years show cross-reactivity with Ganglion ACHR as described in #2 above. I think that what gives me some of my non-typical MG symptoms that coincide with my MG course like severe tinnitis, acid reflux, diarrhea and profuse sweating. All this is controlled by the autonomic nervous system. These other symptoms are worse when the MG is worse or when the mestinon is wearing off and subside when the MG subsides or with a dose of mestinon.
thanks
kathie