I would really appreciate it if you guys could help with this. I have been having the worse cramping in my left foot just about everytime I get on my treadmill in the evening. If I'm just walking I rarely have it but if I get on the treadmill and walk at anything over a slow pace any distane over 1 or 2 tenths of a mile, my foot just cramps and is a real killer. I have not given up but it is pretty discouraging. I can get off sometimes and start again and get in a little more time till it starts again. Does this mean I need more sinemet? I am currently taking 400 mg total, but try to take it earlier in the day to get through my job as normally as possible. Anyway, Have you experienced this, and what have you done, if anything, to help? Thanks much! FG