Be sure you stay well hydrated, too. My mother suffered terribly with leg cramps EVERY night and was prescribed Quinine. It did absolutely NOTHING to help her. I read somewhere that Quinine was frequently prescribed but has proven ineffective. I don't know if that is true but I do know it did nothing to help my mother. I am not sure I spelled the name correctly but I think close enough for people to recognize the drug to which I refer. Wishing you relief. How long has it been since you have had your electrolytes checked via a blood draw? Low potassium is also a culprit. Keep us informed. Wishing you a restful night and pain relief.