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08-30-2016, 10:41 AM | #11 | |||
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Grand Magnate
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The journal papers in the table in previous post (and included in here), are the ones I use to argue ALS median is ordinarily slightly below three years for symptom onset.
Table of ALS datasets |
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09-13-2016, 04:50 PM | #12 | |||
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Grand Magnate
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bump . . . so the is easy to find due to historical information and
includes reference to the growing national database . . . : CDC – National Amyotrophic Lateral Sclerosis (ALS) Registry |
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10-31-2016, 07:23 AM | #13 | |||
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Grand Magnate
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At least two of the studies in the list might have median life expectancy above 51 months, Taiwan's 1149 and Scandinavia's 155 (72). Eleven others remain undiscovered.
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11-09-2016, 02:54 PM | #14 | |||
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Grand Magnate
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(this post is intended for a different thread but I left it here also).
Further to the immediately preceding post . . . the original Phase II study's median was 56 months (n=84), about five months more than RespiTrimALS 51 months (n=37) in their treatment group. I am not sure I understand their specification for the non-stimulation group - it seems to be more then ten years. I just discovered the Scandinavia study (n=155) was of PMA patients rather than ALS patients, 72 months. Taiwan's was 66.6 months for (n=1149) where 241 patients were on a tracheostomy. Protocol for diaphragm pacing in patients with respiratory muscle weakness due to motor neurone disease (DiPALS): a randomised controlled trial | BMC Neurology | Full Text Here again is an URL for crude table of studies . . . (n= ) follows the author's name in each row and the next number to the right is survival (either median or average). Although some are unknown, most are 36 months or less: Table of ALS datasets Hence, superficially, RespiTrimALS results appear significantly better than normal. |
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