[MuonOne]

Its the day before to rise of the dead . . . Halloween!

A fitting time to point out ALS is likely to develop a notorious reputation for producing both 'false-positive' and 'false-negative' results in trials of prospective treatments. For most of the world, especially in the times prior to the recent century, patients went untreated and survivals were known to range from a few months to a few decades. I keep thinking about a 'slogan' found in the expression of the late Seymour Cray, known for building some of the fastest computers . . . (not yours probably) . . . his computers did not deploy safety circuits, such a parity checking, . . . when asked to explain, he said "If you don't believe the results, run it again!" I was reluctant to make the reference because Cray died in a car accident . . . an activity where humans probably most routinely take their greatest risks. How powerful is the spoof-effect of ALS?

. . . May your Halloween be spooky.