pacer Candidates Only ALS spreadsheet:
new dew als - Google Drive

These totals represent only patients who mentioned the pacer, whether they obtained one or not . . . earlier edition included patients simply because they are famous patients even if they never mentioned the pacer and thus I do not know if they used one . . . You can see, while there are more patients who commented on the web regarding the pacer but did not try than there are who tried and shows those who tried seem to be surviving longer . . . more on this issue later.

The current differences at the five and eight year thresholds are especially interesting in the table in the previous post: they show the pacer being ahead at the raw score level even though there were many more non-declared patients (who most likely did not try the pacer). When scaled for crude correction of the gap created by substantially different number of patients in each group, the pacer is ahead at every threshold except the twenty-year threshold and tied in every bracket zone except the 7,000 to 7,306 bracket zone.

Have a nice weekend!

I’m a neuroscientist who taught rats to drive − their joy suggests how anticipating fun can enrich human life

I’m a neuroscientist who taught rats to drive − their joy suggests how anticipating fun can enrich human life | CNN

This news story, perhaps unwittingly, provides a review of in vivo research and unexpected insights for a brief diversion of the often boring run of the mill (punny?)

World's Best Hospitals 2024
World's Best Hospitals 2024 - Newsweek Rankings

Best-in-State Hospitals 2025
America's Best in-State Hospitals 2025 - Newsweek Rankings

World Rankings
1 Mayo Clinic
2 Cleveland Clinic (across the street from University Hospital)
4 Johns Hopkins
5 Massachusetts General Hospital
19 Brigham and Women's Hospital
60 Mayo Clinic Jacksonville

154 University Hospitals, Cleveland

United Kingdom Hospitals making the World Rankings are these:
36 St. Thomas
83 Guy's
84 University College
91 Addenbrooke
112 John Radcliffe
{Cleveland's University Hospitals is 154 and would appear here and is the location of the lead surgical team in β-phragmatic pacing in Amyotrophic Lateral Sclerosis patients}
174 Royal Victoria
179 Chelsea Westminster
184 St. Bartholomew
210 Queen Elizabeth Birmingham
227 Freeman
231 King's College

As near as I can tell, none of the United Kingdom hospitals involved in the Amyotrophic Lateral Sclerosis β-phragmatic pacing trial made the World's Best Hospitals rankings:
University of Sheffield: Christopher J McDermott (chief investigator), Pamela J Shaw (principal investigator), Cindy L Cooper, Simon Dixon, Wendy O Baird, Mike J Bradburn, Patrick Fitzgerald, Chin Maguire;
Newcastle-upon-Tyne Hospitals NHS Foundation Trust: Tim Williams (principal investigator), Simon V Baudouin, Dayalan Karat;
Oxford University Hospitals NHS Trust: Kevin Talbot (principal investigator), John Stradling, Nick Maynard, Martin Turner;
Sheffield Teaching Hospitals NHS Foundation Trust: Stephen Bianchi, Roger Ackroyd; Northumbria Healthcare NHS Foundation Trust: Stephen C Bourke;
Salford Royal Hospital NHS Foundation Trust: John Ealing, Hisham Hamdalla;
University Hospital of South Manchester NHS Foundation Trust: Andrew Bentley (principal investigator), Simon Galloway;
Royal Free London NHS Foundation Trust: Richard W Orrell (principal investigator), Wisia Wedzicha;
Leeds Teaching Hospitals NHS Trust: Mark Elliot;
Plymouth Hospitals NHS Trust: Philip Hughes; Plymouth University Peninsula Medical and Dental Schools: C Oliver Hanemann.

- - - - >>>> HOWEVER, I am still working on the details of my review on this point . . . !

I want to wish you a happy Thanksgiving . . .
I wonder which will happen first . . . completion of my Food Museum . . . or . . . cure for Amyotrophic Lateral Sclerosis found . . . of course, to the best of my knowledge and belief, neither exist at this time.

I read an article recently, which indicated turkey is not very popular . . . what about . . . ?

Maybe one day we will all be g-tubing 'purrfect' nutrition!

About thirty patients are included in my dataset for reasons of their famousness rather than any comment they made regarding the Amyotrophic Lateral Sclerosis pacer intervention . . . the chart with most of these patients removed looks almost like:
update alpha als - Google Drive
I suggest noting the eight and five year thresholds, which show pacing patients raw score 'defeating' patients who are not known implantees even though the pacing patients were far fewer in number than those not known to have paced but are known considerers of pacing. The cases beyond the Texas threshold (TX) are very few and not likely statistically significant at this time but statistics can be true even if they have not reached statistical significance.

Happy Holidays!

I just counted, I think thirty-three of the patients included in my dataset are actually famous patients rather patients included by virtue of indicating an interest in pulmonary pacing as a possible intervention. There are about four hundred patients in the list, most ultimately didn't pace but at least one hundred and eight-one did. Only the twenty year survival category has the pacer falling short of historical controls but by very little . . . the next patient is very near the threshold at this moment and may have crossed it. This patient is also famous among Amyotrophic Lateral Sclerosis patients. I am expecting the pacing group to be ahead of the non-pacing group in all historically recognized categories by next year. I am working on the 'by how much' analysis as I type this message.

At the recent NeuroTech 2024 Angelique Paulk addressed the issue of new brain implants. Reports were made regarding the possibility breathing signals can be detected via brain implants, such as Utah implants, . . . potentially resolving concerns of asynchrony between the pacer and the natural breathing signals. Such could provide improved breathing performance but would require further surgery.

from: DAGMAR MUNN
When things go right: My week living with ALS
ALS and Wellness Blog: When things go right: My week living with ALS

As we know, Dr. Bedlack investigates large scale ALS reversals; Dagmar describes a single muscle reversal they encountered recently . . . their gluteus medius muscle, involved in hip movements. Undoubtedly, single muscle fiber reversals may occur also.

Herb Chambers makes massive, $100M gift to Mass General Hospital to fund cancer care

Herb Chambers makes $100M gift to Mass General Hospital

This story is so nice I just had to post it . . . sometimes Amyotrophic Lateral Sclerosis symptoms really are cancer . . . I know of a few misdiagnosed cases. I hope Christmas time is this great for many others.