FAQ/Help |
Calendar |
Search |
Today's Posts |
08-22-2007, 05:51 AM | #1 | ||
|
|||
New Member
|
I would like to know why amyloid plaques (deposits in the brain of a sticky protein called amyloid beta peptide) "causes" neurodegeneration? I am aware that it doesn't directly CAUSE neurodegenerenation, but I want to know why that protein is so special in Alzheimer's Disease. Do neurons die because of it?
If I were to say that Alzheimer's Disease is a Tauopathy, I would be saying that it is "caused" by neurofibrilary tangles (overexpression of tau protein), right? So this amyloid plaque would not be that relevant? Research done in this area, in tauopathies, has the aim of trying to find out a drug, compound, that will have a positive effect on reducing the amount of tau protein produced in the brain. Would this be a possible cure for Alzheimer's Disease and other tauopathies? Why do we want to reduce the amount of tau protein produced in the brain? To see if it is the cause of neurodegenerative diseases? Please help. Do answer. Even if you do not have any good knowledge on this matter, I would like to know what you think and what makes sense to you. It can get me started. Thanks for at least reading |
||
Reply With Quote |
08-22-2007, 03:50 PM | #2 | |||
|
||||
Legendary
|
Hi there,
I have no idea how to answer your questions. I had 2 close family members who had Alzheimer's Disease but my knowledge is very basic in this area except for my fear of actually getting it. :/ I just wanted to alert you to a couple of areas of information. One I just read in the Health News Forum here this morning and there are some more links on the Psych Central site as well. The news item I just read today was specificially related to Tau. Down on the bottom of the PsychCentral url, the 2nd one, you'll find more Related Clinical Articles. Quote:
http://psychcentral.com/news/2007/08...ine-effective/ Quote:
Quote:
|
|||
Reply With Quote |
Reply |
|
|