Parkinson's Disease Tulip


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Old 09-22-2009, 07:47 AM #1
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Default Can Over-the-counter Vitamin-like Substance -- Coenzyme Q10 -- Slow Progression Of PD

Can Over-the-counter Vitamin-like Substance -- Coenzyme Q10 -- Slow Progression Of Parkinson's Disease?

http://www.sciencedaily.com/releases...0921143147.htm

ScienceDaily (Sep. 21, 2009) — Rush University Medical Center is participating in a large-scale, multi-center clinical trial in the U.S. and Canada to determine whether a vitamin-like substance, in high doses, can slow the progression of Parkinson's disease, a neurodegenerative disorder that affects about one million people in the United States.

"At present, the very best therapies we have for Parkinson's can only mask the symptoms – they do not alter the underlying disease," said neurologist Dr. Katie Kompoliti, a specialist in movement disorders. "Finding a treatment that can slow the degenerative course of Parkinsons's is the holy grail of Parkinson's research."

The substance being tested, called coenzyme Q10, is produced naturally in the body and is an important link in the chain of chemical reactions that produce energy in mitochondria, the "powerhouses" of cells. The enzyme is also a potent antioxidant – a chemical that "mops up" potentially harmful chemicals generated during normal metabolism.
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Old 09-22-2009, 10:43 AM #2
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Default coenzyme q10, mitochondrial dysfunction and PD

concept for this clinical trial is based upon a small study reported in Oct, 2002.
http://www.scienceblog.com/cms/coenz...nsons_in_study

Coenzyme Q10 slows Parkinson's in study
High doses of the naturally occurring compound coenzyme Q10 has been found to slow by 44 percent the deterioration in function that occurs in Parkinson's disease. The greatest benefit was seen in everyday activities like eating, dressing, bathing and walking. But researchers say that before people run out to RightAid for a barrel of the stuff, a wider study is needed (this one tracked 80 patients)
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Old 09-22-2009, 01:47 PM #3
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Default The Holy Grail? Indeed!

Slowing the progression is the HG? Is it just me, or is this another reflection of the lack of urgency problem? How about a cure, doc?
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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