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Old 03-06-2009, 01:10 PM #1
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Default "stress neurodegeneration and individual differences" video

http://video.google.com/videoplay?do...67554618436978

'Stress, Neurodegeneration and Individual Differences' by Robert Sapolsky
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Old 03-06-2009, 04:02 PM #2
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But at an hour and twenty minutes you've really gotta be dedicated (OK, obsessed) so, here is the synoposis-

Neurons don't just die. They sort of have bad days where a series of things go wrong. Normally they can recover from, say, that whiff of pesticide. Or that hypoglycemic episode. Or half-a-dozen other "insults."

Each of those insults is actually a short chain of events (the ever-popular "cascade"), maybe five or six. But we can usually handle it. However, if we are awash in gluccocorticoids (i.e. cortisol) each of those events is amplified and once each step in the chain is ramped up you no longer have a recovering neuron you have a dead one. So, chill!


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Originally Posted by olsen View Post
http://video.google.com/videoplay?do...67554618436978

'Stress, Neurodegeneration and Individual Differences' by Robert Sapolsky
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 03-07-2009, 01:37 AM #3
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really enjoyed several of his quotes--favorite one: "What's the punch line here? Physiologically, it doesn't come cheap being a bastard 24 hours a day." Dr. Robert Sapolsky, "Stress, Neurodegeneration and individual differences".
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The future is already here — it's just not very evenly distributed. William Gibson
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