I've tried so many arthritis supplements but the UCII product was suggested by a friend who sent her sister a bottle to start with, her sister deals with RA, and my friend got a bottle for herself as her knee is giving her fits (osteo)...so I've added this to my nightly regime...one close to bed:

http://www.jissn.com/content/10/1/48

Price is right and I'm using Now UCII. Wouldn't it be great to get some more relief.

I'm closing in on 2 months on UCII and believe it's giving me some support. Long time chronic joint issues don't change overnight. Price is right to stay with it.

Well, I'm in 3rd month with UCII and feeling pretty good, improvement I believe. One bottle is two months worth. Still taking 1 before bed.

I just talked to now foods product consultant about taking more and probably no need. She said their clinical trials were based on 1 before bed. Depending too on how advanced OA is, relief can take longer or shorter time. Foods we need to eliminate..she did mention working to eliminate gluten which I do a lot.

Then she said taking with Celedrin could help too. Celedrin addresses pain while UCII addresses collagen growth. I've taken Celedrin over the years but may look into it again to take with UCII.

But, so far, liking this collagen product. C

Are you eating the undenatured collagen?

If so, it will be broken down into its (very common and non-essential) amino acids by digestive enzymes in the gut in just the same way as any other protein that you eat.

It is very unlikely that an intact protein like collagen can cross the gut wall, entering the bloodstream and equally unlikely that it can pass from the bloodstream into cells of a tissue where it might be of putative benefit.

No Kiwii I'm not eating undenatured collagen. I take a 40mg capsule of the UCII nightly now into my 3rd month. Here is info from Scripps San Diego. I'll give it at least 3 more months. I have said this before, I'll do all I can to NOT do a surgery on my knee. I pay dearly for a hip job that I didn't plan on. I expected quite the opposite.

http://newhope360.com/ingredients/ne...benefits-uc-ii

Caroline, thank you for that link - it was very interesting.

I agree that eating glucosamine hydrochloride or chondroitin sulfate may help people with osteoarthritis,

However, I disagree with you about UC-II, which seems to a registered trade-name for undenatured collagen. A quick Google shows that there are many comp/alt med sites which offer to sell it.

Eating collagen (it does not matter if it is denatured or not) makes no sense as treatment for osteoarthritis.

A close analogy which may help you;

People with Type 1 diabetes need daily doses of insulin to stay alive. Those doses are delivered by injection. Eating insulin would
be pointless - it would (in the same way as any other protein) be broken down into its amino acids in the gut with no therapeutic benefit. That is why people who need insulin do not eat it.

Eating collagen is just as pointless for somebody with osteoarthritis as it is for somebody with Type 1 diabetes eating insulin.