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Old 11-28-2007, 09:13 AM #1
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mrsD mrsD is offline
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Default a serious warning sign...

Sorry to be late to this thread---but alot of research was needed to bring facts here.

When a parent company withdraws a drug voluntarily from the US market, beware.

This is done to avoid liability. Luvox is no longer available in US from Solvay.
The drug is available as fluoxamine generic. Should you need to sue for damages, Solvay is not liable any longer.
Solvay sold their patent to another company JAZZ. (Somehow this name is rather disturbing for a drug company! (It is a subsidiary of Solvay however).

Quote:
In January 2007, Jazz Pharmaceuticals licensed from Solvay Pharmaceuticals the right to market Luvox CR and Luvox in the United States. Solvay Pharmaceuticals retains the right to market both products in other territories around the world. Subject to receipt of FDA approval, Jazz Pharmaceuticals expects to launch Luvox CR in the United States during the first quarter of 2008.
from http://www.emaxhealth.com/94/14611.html

and this link:
http://www.reuters.com/article/compa...EN009220070802

http://www.fda.gov/bbs/topics/ANSWER.../ANS01283.html
(2004)

At the time Luvox was approved here, there was a situation with one of the trial doctors who falsified information.

Medwatch data:
http://www.fda.gov/medwatch/safety/2000/jun00.htm#luvox
serious issues.

Here is a link to reported serious events with fluvoxamine in 2007:
http://patientsville.com/medication/...de_effects.htm
Keep in mind it is not commonly used, so the reports are few.
But the ones there are pretty serious.

Luvox was in the news heavily about the Columbine shootings. There is information on the net suggesting one of the young men was using this drug in high doses. A lawsuit resulted. Mania and psychosis are in the drug information side list for Luvox.

Since fluvoxamine has more specificity for serotonin receptors, the side effects of suicide and aggression may be higher, IMO for it.

This drug certainly has a checkered past. I would be hesitant to put my child on it for any reason.

As an aside: L-tryptophan is now available without prescription in US (since this summer). You can discuss with
your doctor trying this to raise serotonin more gently--and it works best with B6 added too.
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